Effects of lycium on liver cellular ultrastructure and antioxidant activity of rats under tolerance training / 生物医学工程学杂志

ABSTRACT

64 eight-week-old female rats were randomly divided into to 8 groups with four in medical treatment group and four in control group. The treatment groups were trained by progressive intensifying endurance swimming, and the medical-taken groups were fed with lycium for 5 weeks, and then the changes of the liver cellular free radical metabolism and ultrastructure were investigated. The effects of lycium and endurance training on liver cellular ultrastructure and free radical metabolism in rats were then explored. The results showed that exhaustive swimming time of rats could be extended by endurance training, and that exhaustive swimming time of rats could significantly be prolonged after taking lycium, and the ultrastructure of liver cell with taking lycium was more complete than that without taking lyceum. Lycium could cause significant increase of the activity of liver superoxide dismutase (SOD) and the ratio of SOD/MDA, and meanwhile cause decrease of the content of liver MDA. Conclusions can be drawn that lycium and endurance training can improve exercise capacity of rats, and lycium has certain protecting functions of the liver.