Effect of short-term intensive therapy with glimepiride and metformin in newly diagnosed type 2 diabetic patients / 南方医科大学学报
Journal of Southern Medical University
; (12): 564-566, 2011.
Article
em Zh
| WPRIM
| ID: wpr-307884
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the effect of short-term intensive therapy on blood glucose control, BETA-cell function, and blood lipid levels in newly diagnosed type 2 diabetic patients.</p><p><b>METHODS</b>Out-patients with newly diagnosed type 2 diabetic patients were enrolled for intensive treatment with sulfonylureas and metformin for 12 weeks, and the therapeutic effect was evaluated.</p><p><b>RESULTS</b>After the intensive treatment, FPG, 2 hPG, and HbA1c decreased significantly (P<0.01); HOMA-IR decreased and HOMA-B increased significantly (P<0.01), and TG, CHOL, LDL decreased significantly (P<0.01) after the treatment.</p><p><b>CONCLUSION</b>Short-term intensive treatment with glimepiride combined with metformin is safe and effective in newly diagnosed type 2 diabetic patients with HbA1c>9%.</p>
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Compostos de Sulfonilureia
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Resultado do Tratamento
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Usos Terapêuticos
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Diabetes Mellitus Tipo 2
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Tratamento Farmacológico
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Quimioterapia Combinada
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Metformina
Limite:
Female
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Humans
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Male
Idioma:
Zh
Revista:
Journal of Southern Medical University
Ano de publicação:
2011
Tipo de documento:
Article