Qualitative analysis of a sulfur-fumigated Chinese herbal medicine by comprehensive two-dimensional gas chromatography and high-resolution time of flight mass spectrometry using colorized fuzzy difference data processing / 中国结合医学杂志
Chinese journal of integrative medicine
; (12): 261-269, 2017.
Artigo
em Inglês
| WPRIM (Pacífico Ocidental)
| ID: wpr-310836
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the chemical transformation of volatile compounds in sulfur-fumigated Radix Angelicae Sinensis.</p><p><b>METHODS</b>A comprehensive two-dimensional gas chromatography (GC×GC) and high-resolution time-of-flight mass spectrometry (HR-TOF/MS) with colorized fuzzy difference (CFD) method was used to investigate the effect of sulfur-fumigation on the volatile components from Radix Angelicae Sinensis.</p><p><b>RESULTS</b>Twenty-five compounds that were found in sun-dried samples disappeared in sulfur-fumigated samples. Seventeen volatile components including two sulfur-containing compounds were newly generated for the first time in volatile oils of sulfur-fumigated Radix Angelicae Sinensis.</p><p><b>CONCLUSION</b>The strategy can be successfully applied to rapidly and holistically discriminate sun-dried and sulfur-fumigated Radix Angelicae Sinensis. GC×GC-HR-TOF/MS based CFD is a powerful and feasible approach for the global quality evaluation of Radix Angelicae Sinensis as well as other herbal medicines.</p>
Texto completo:
Disponível
Contexto em Saúde:
ODS3 - Saúde e Bem-Estar
Problema de saúde:
Meta 3.3: Acabar com as doenças tropicais negligenciadas e combater as doenças transmissíveis
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Padrões de Referência
/
Enxofre
/
Óleos Voláteis
/
Medicamentos de Ervas Chinesas
/
Fumigação
/
Lógica Fuzzy
/
Cor
/
Compostos Orgânicos Voláteis
/
Cromatografia Gasosa-Espectrometria de Massas
/
Métodos
Tipo de estudo:
Pesquisa qualitativa
Idioma:
Inglês
Revista:
Chinese journal of integrative medicine
Ano de publicação:
2017
Tipo de documento:
Artigo