Human umbilical cord mesenchymal stem cells and the treatment of spinal cord injury / 中华医学杂志(英文版)
Chinese Medical Journal
; (24): 225-231, 2009.
Artigo
em Inglês
| WPRIM (Pacífico Ocidental)
| ID: wpr-311887
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To review the recent studies about human umbilical cord mesenchymal stem cells (hUCMSCs) and advances in the treatment of spinal cord injury. Data sources Published articles (1983 - 2007) about hUCMSCs and spinal cord injury were selected using Medline. Study selection Articles selected were relevant to development of mesenchymal stem cells (MSCs) for transplantation in spinal cord injury therapy. Of 258 originally identified articles 51 were selected that specifically addressed the stated purpose.</p><p><b>RESULTS</b>Recent work has revealed that hUCMSCs share most of the characteristics with MSCs derived from bone marrow and are more appropriate to transplantation for cell based therapies.</p><p><b>CONCLUSIONS</b>Human umbilical cord could be regarded as a source of MSCs for experimental and clinical needs. In addition, as a peculiar source of stem cells, hUCMSCs may play an important role in the treatment of spinal cord injury.</p>
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Patologia
/
Fisiologia
/
Traumatismos da Medula Espinal
/
Terapêutica
/
Cordão Umbilical
/
Biologia Celular
/
Transplante de Células-Tronco
/
Células-Tronco Mesenquimais
/
Modelos Biológicos
Tipo de estudo:
Estudo prognóstico
Limite:
Humanos
Idioma:
Inglês
Revista:
Chinese Medical Journal
Ano de publicação:
2009
Tipo de documento:
Artigo