Risk factors for intracranial hemorrhage in very low birth weight infants / 中国当代儿科杂志
Chinese Journal of Contemporary Pediatrics
; (12): 297-300, 2007.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-312714
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To study the risk factors for intracranial hemorrhage in very low birth weight infants.</p><p><b>METHODS</b>Data from 169 very low birth weight (VLBW) infants (birth weight 1000-1500 g; gestational age 23-36 weeks) were studied retrospectively. Twenty-nine perinatal and postnatal factors were analyzed by Crosstabs Test with SPSS 12.0. A logistic regression analysis was used to identify the risk factors associated with the development of intracranial hemorrhage.</p><p><b>RESULTS</b>Multivariate logistic analysis revealed that rupture of membranes (OR=0.146, 95%CI=0.22-0.964, P < 0.05), 1-minute Apgar score < or = 7 (OR=0.112, 95%CI=0.21-0.591, P < 0.01), pulmonary surfactant therapy (OR=0.110, 95%CI=0.24-0.504, P < 0.01), mechanical ventilation therapy (OR =0.076, 95%CI=0.009-0.668, P < 0.05), mechanical ventilation duration > 72 hrs(OR=0.053, 95%CI=0.007-0.410, P < 0.01), prothrombin time > 20 seconds (OR=4.186, 95%CI=1.606-10.923, P < 0.01), pH value on day 1 of life < 7.25 (OR=0.421, 95%CI=0.179-0.995, P < 0.05) and hyponatremia on day 1 (OR= 0.27, 95%CI=0.077-0.940, P < 0.05) or 2 (OR=2.480, 95%CI=1.053-5.838, P < 0.05) of life were risk factors for intracranial hemorrhage.</p><p><b>CONCLUSIONS</b>1-minute Apgar score < or =7 and mechanical ventilation treatment were leading risk factors for intracranial hemorrhage, followed by abnormal coagulation and electrolytes related to perinatal asphyxia in VLBW infants. These findings can be used to improve the surveillance and prophylaxis measures in VLBW infants at high risk.</p>
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Modelos Logísticos
/
Fatores de Risco
/
Recém-Nascido de muito Baixo Peso
/
Hemorragias Intracranianas
Tipo de estudo:
Estudo de etiologia
/
Estudo prognóstico
Limite:
Feminino
/
Humanos
/
Masculino
/
Recém-Nascido
Idioma:
Chinês
Revista:
Chinese Journal of Contemporary Pediatrics
Ano de publicação:
2007
Tipo de documento:
Artigo