Treatment of refractory severe autoimmune disease by combined therapy with Chinese drug and autohemopoietic stem cell transplantation / 中国中西医结合杂志
Chinese Journal of Integrated Traditional and Western Medicine
; (12): 212-215, 2008.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-315165
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the clinical effect of Chinese herbal medicine combined with auto-hemopoietic stem cell transplantation for refractory severe autoimmune disease (RSAID).</p><p><b>METHODS</b>Auto-hemopoietic stem cell transplantation was conducted for the treatment of 7 patients with RSAID, including 4 cases of systemic lupus erythematosus (SLE), 2 myasthenia gravis (MG) and 1 polymyositis (PM) with the FAC program (consisting of fludarabine, antithymocyte globulin, and cyclophosphamide FAC) as for pretreatment. Traditional Chinese medicine (TCM) was given orally after transplantation to patients according to their syndrome type.</p><p><b>RESULTS</b>The hemopoiesis function was smoothly re-established in all patients, with their clinical symptoms and signs obviously improved, laboratory indexes negatively conversed or obviously decreased, and withdrawal or dose reducing of medicines.</p><p><b>CONCLUSION</b>Combined use of TCM after auto-hemopoietic stem cell transplantation can accelerate patients' hemopoiesis function re-establishment, with significant effects in reducing complications, improving clinical symptoms and signs.</p>
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Doenças Autoimunes
/
Terapêutica
/
Transplante Autólogo
/
Vidarabina
/
Medicamentos de Ervas Chinesas
/
Resultado do Tratamento
/
Terapia Combinada
/
Transplante de Células-Tronco Hematopoéticas
/
Usos Terapêuticos
/
Quimioterapia Combinada
Limite:
Adolescente
/
Adulto
/
Feminino
/
Humanos
/
Masculino
Idioma:
Chinês
Revista:
Chinese Journal of Integrated Traditional and Western Medicine
Ano de publicação:
2008
Tipo de documento:
Artigo