Analysis of death causes of 345 cases with HIV/AIDS in Guangdong area / 中华实验和临床病毒学杂志
Chinese Journal of Experimental and Clinical Virology
; (6): 57-60, 2013.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-318104
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To analyze the death causes of 345 cases with HIV/AIDS in Guangdong area.</p><p><b>METHODS</b>The situations of 345 hospitalized death cases with HIV/AIDS were conducted by retrospective analysis.</p><p><b>RESULTS</b>(1)There were total 3406 hospitalized cases with HIV/AIDS in a hospital from January 2001 to December 2011 and 345 cases died, the fatality rate was 10. 13%. Since 2005 the introduction of free anti-viral treatment, the fatality rate of HIV/AIDS declined. The fatality rate of the patients whose CD4+ T lymphocyte counts <200 cells/microl was 14.61% (299/2046) and it was significantly higher than that of patients whose CD4 T lymphocyte counts >or=200 cells/microl (P <0.01). (2) 99.42% of the death cases had more than one kind of opportunistic infections (OI) and there were 924 cases of OI totally. 84. 64% of OI related to the death directly. Fungal infection was the most common in OI, followed by bacterial infection. Most OI occurred in the lungs, mouth, other systemic disseminated diseases, gastrointestine, central nerver system, septicemia, skin. The AIDS defining opportunistic infections such as several pneumonia, disseminated penicilliosis marneffei and CNS infections accounted for 29.65%. Other factors that caused HIV/AIDS death included opportunistic tumors, HIV related disease and non AIDS-related disease accounted for 15.36%. No accepted effective highly active antiretroviral therapy (HARRT) also constituted factors of death. Among cases which accepted HARRT treatment, only 6.96% had the period of treatment over three months.</p><p><b>CONCLUSION</b>The fatality rate of end-stage AIDS patients was high and the opportunistic infections was the most important cause of death. Early diagnosis and treatment for opportunistic infections, timely effective HARRT were the key to improve the quality of life of AIDS patients.</p>
Texto completo:
Disponível
Contexto em Saúde:
ODS3 - Saúde e Bem-Estar
/
ODS3 - Meta 3.3 Acabar com as doenças tropicais negligenciadas e combater as doenças transmissíveis
/
ODS3 - Meta 3.2 Reduzir as mortes de recém nascidos e crianças com menos de 5 anos
Problema de saúde:
Meta 3.3: Acabar com as doenças tropicais negligenciadas e combater as doenças transmissíveis
/
Meta 3.2: Reduzir as mortes de recém nascidos e crianças com menos de 5 anos
/
AIDS
/
Infecções
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Infecções por HIV
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China
/
Epidemiologia
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Estudos Retrospectivos
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Mortalidade
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Causas de Morte
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Síndrome da Imunodeficiência Adquirida
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Contagem de Linfócito CD4
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Tratamento Farmacológico
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Alergia e Imunologia
Tipo de estudo:
Estudo de etiologia
/
Estudo observacional
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Estudo prognóstico
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Estudo de rastreamento
Aspecto:
Preferência do paciente
Limite:
Adolescente
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Adulto
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Criança
/
Criança, pré-escolar
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Feminino
/
Humanos
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Lactente
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Masculino
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Recém-Nascido
País/Região como assunto:
Ásia
Idioma:
Chinês
Revista:
Chinese Journal of Experimental and Clinical Virology
Ano de publicação:
2013
Tipo de documento:
Artigo