Role of immunologic abnormality in recurrent parotitis in children / 浙江大学学报·医学版
Journal of Zhejiang University. Medical sciences
; (6): 419-423, 2010.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-319883
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the relationship between immune function and the recurrent parotitis (RP) for children.</p><p><b>METHODS</b>The children diagnosed as RP were divided into two groups aged under 6y and over 6y and the immune function were measured and compared with that of normal children.</p><p><b>RESULTS</b>For RP children the ratio of CD4+ T cell in over 6y group was significantly lower than that in under 6y group (P<0.05), while IgG value in over 6y group was higher than that in under 6y group (P<0.05). Compared with normal children, RP children in under 6y group had higher CD8+ T cell ratio and IgG, IgE, IgA and C3 value (P<0.01) and lower CD4+ T cell ratio (P<0.01), while RP children over 6y group, they had higher CD8+ T cell ratio, IgE value (P<0.01) and C3 (P<0.05), lower CD4<T cell ratio than those in control group (P<0.01). IgE value and CD8+ T cell ratio in under 6y group were higher than those over 6y control group (P<0.01).</p><p><b>CONCLUSION</b>Impaired immune function may play an important role in the recurrent parotitis in children.</p>
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Parotidite
/
Recidiva
/
Sangue
/
Imunoglobulina A
/
Imunoglobulina E
/
Imunoglobulina G
/
Linfócitos T CD4-Positivos
/
Relação CD4-CD8
/
Biologia Celular
/
Alergia e Imunologia
Limite:
Criança
/
Criança, pré-escolar
/
Feminino
/
Humanos
/
Lactente
/
Masculino
Idioma:
Chinês
Revista:
Journal of Zhejiang University. Medical sciences
Ano de publicação:
2010
Tipo de documento:
Artigo