Diagnostic value of strain index in prostate peripheral zone lesions by real time tissue elastography / 中国医学科学院学报

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the value of strain index (SI) by transrectal real-time tissue elastography (TRTE) for differentiation of the prostate peripheral zone lesions.</p><p><b>METHODS</b>Totally 83 patients with suspected prostate cancer underwent the quantitative analysis by TRTE examination. The SI of total lesions (ASI) and peak elasticity in lesion (PSI) were calculated, and the pathologic findings were compared. Then the values of ASI and PSI in the differential diagnosis of prostate lesions were assessed. The influence of Gleanson scores on SI was evaluated.</p><p><b>RESULTS</b>The area under the Receiver Operating Characteristic curves (or ROC curves) of ASI and PSI were 0.62 (P=0.06) and 0.92 (P=0.00) respectively for the differential diagnosis of prostate peripheral lesions. When a cutoff point of 17.44 was used,PSI had a sensitivity of 74.5% and a specificity of 83.3%. Gleason scores showed no significant difference between PSIü 17.44 group and PSIþ17.44 group ( P>0.05).</p><p><b>CONCLUSION</b>PSI is helpful for the differential diagnosis of prostate peripheral zone lesions.</p>