Detection of serum anti-F antibody in hepatitis C virus infected patients / 中华流行病学杂志
Chinese Journal of Epidemiology
; (12): 1116-1118, 2007.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-322879
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To assess the prevalence of serum anti-F in patients with hepatitis C virus (HCV) infection and the distribution of anti-F.</p><p><b>METHODS</b>The recombinant protein (HCV-F/GST) was coated onto micro titer plates as antigen. Sera of 120 patients with hepatitis C virus infection, 15 patients with hepatitis B, 3 patients with hepatitis E and 10 normal sera were tested by indirect ELISA for detecting anti-F.</p><p><b>RESULTS</b>82 samples out of the 120 (68%) HCV infected patients exhibited a positive anti-F reaction, showing significant difference from the controls with no HCV infection (P < 0.01). Data from logistic analysis showed that the positive rate of anti-F was higher in patients over 50 year olds (OR = 6.675, 95% CI 2.407-19.071). Patients of midrange, severe phase and hepatic cirrhosis had higher rate than the others (OR = 2.749, 95% CI 1.470-5.141).</p><p><b>CONCLUSION</b>Prevalence and distribution of anti-F in Yixing hepatitis C patients was reported and which might be related to the progression of HCV infection.</p>
Texto completo:
Disponível
Contexto em Saúde:
ODS3 - Saúde e Bem-Estar
Problema de saúde:
Meta 3.3: Acabar com as doenças tropicais negligenciadas e combater as doenças transmissíveis
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Sangue
/
Ensaio de Imunoadsorção Enzimática
/
Anticorpos Anti-Hepatite
/
China
/
Proteínas do Core Viral
/
Prevalência
/
Hepatite C
/
Hepacivirus
/
Antígenos da Hepatite C
/
Alergia e Imunologia
Tipo de estudo:
Estudo diagnóstico
/
Estudo de prevalência
Limite:
Adulto
/
Feminino
/
Humanos
/
Masculino
País/Região como assunto:
Ásia
Idioma:
Chinês
Revista:
Chinese Journal of Epidemiology
Ano de publicação:
2007
Tipo de documento:
Artigo