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Body mass index and prognosis in patients with systolic heart failure / 中华心血管病杂志
Chinese Journal of Cardiology ; (12): 870-874, 2009.
Artigo em Chinês | WPRIM (Pacífico Ocidental) | ID: wpr-323933
Biblioteca responsável: WPRO
ABSTRACT
<p><b>OBJECTIVE</b>In individuals without cardiovascular disease, elevated body mass index (BMI) is associated with an increased risk of death. However, in patients with certain chronic diseases, including heart failure, low BMI has been associated with increased mortality. We investigated the association between BMI and prognosis in patients with systolic HF.</p><p><b>METHOD</b>Follow-up was made on 540 patients (mean age 58.53 years, 84.2% men) with systolic HF (LVEF < or = 45%) and association between BMI and adverse cardiac events was analyzed.</p><p><b>RESULTS</b>During a median follow-up of 24 months, 92 patients died including 87 cases of cardiac death and 92 patients were rehospitalized. Compared with patients with BMI higher than 28.0 kg/m(2), patients in lower BMI categories (BMI < or = 18.5 kg/m(2) and > or = 18.5 kg/m(2) < 24.0 kg/m(2)) had a graded increase in the all cause death rate [5.44 (1.78 - 16.66), 4.30 (1.71 - 10.82)], cardiac death rate [OR(95%CI) 5.42 (1.77 - 16.59), 4.00 (1.59 - 10.10)], HF death rate [8.94 (2.37 - 33.74), 4.97 (1.52 - 16.20)] and MACE rate [2.10 (1.09 - 4.07), 1.79 (1.14 - 2.82)]. After adjustment for age, gender, LVEF and NYHA grade using cox regression analysis, BMI categories still significantly associated with all cause death rate (OR = 0.77, P < 0.05), cardiac death rate (OR = 0.78, P < 0.05) and HF death rate (OR = 0.79, P < 0.05).</p><p><b>CONCLUSION</b>In patients with systolic heart failure, lower BMI was an independent predictor of increased all cause death rate, cardiac death rate and HF death rate.</p>
Assuntos
Texto completo: Disponível Contexto em Saúde: ODS3 - Meta 3.4 Reduzir as mortes prematuras devido doenças não transmissíveis Problema de saúde: Doença Cardiovascular / Obesidade / Outras Doenças Circulatórias Base de dados: WPRIM (Pacífico Ocidental) Assunto principal: Prognóstico / Índice de Massa Corporal / Seguimentos / Mortalidade / Causas de Morte / Insuficiência Cardíaca Sistólica Tipo de estudo: Estudo observacional / Estudo prognóstico / Fatores de risco Limite: Adulto / Idoso / Humanos / Masculino Idioma: Chinês Revista: Chinese Journal of Cardiology Ano de publicação: 2009 Tipo de documento: Artigo
Texto completo: Disponível Contexto em Saúde: ODS3 - Meta 3.4 Reduzir as mortes prematuras devido doenças não transmissíveis Problema de saúde: Doença Cardiovascular / Obesidade / Outras Doenças Circulatórias Base de dados: WPRIM (Pacífico Ocidental) Assunto principal: Prognóstico / Índice de Massa Corporal / Seguimentos / Mortalidade / Causas de Morte / Insuficiência Cardíaca Sistólica Tipo de estudo: Estudo observacional / Estudo prognóstico / Fatores de risco Limite: Adulto / Idoso / Humanos / Masculino Idioma: Chinês Revista: Chinese Journal of Cardiology Ano de publicação: 2009 Tipo de documento: Artigo
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