Determination of beta-endorphin in hypothalamus of rat with primary trigeminal neuralgia / 中华口腔医学杂志

ABSTRACT

<p><b>OBJECTIVE</b>To determine the level and the role of beta-endorphin in hypothalamus of rat with trigeminal neuralgia.</p><p><b>METHODS</b>The animal model of primary trigeminal neuralgia in rat was established, the contents of beta-endorphin were measured by radioimmunoassay techniques.</p><p><b>RESULTS</b>The beta-endorphin of hypothalamus in experimental group was significantly lower than other groups (P < 0.01).</p><p><b>CONCLUSIONS</b>Beta-endorphin may play important roles in primary trigeminal neuralgia.</p>