Estimation of Microalbuminuria by Urinary Albumin to Creatinine Concentration Ratio / 대한진단검사의학회지
The Korean Journal of Laboratory Medicine
; : 109-112, 2003.
Artigo
em Coreano
| WPRIM (Pacífico Ocidental)
| ID: wpr-32430
Biblioteca responsável:
WPRO
ABSTRACT
BACKGROUND:
Microalbuminuria is the main parameter used in diabetic patients for clinical evaluation of early diabetic nephropathy and other complications. The most common method for quantitative urinary protein relies on a 24-hour urine collection or overnight urine collection; however, this method is time consuming and sometimes obtains inaccurate results. This study is aimed to test whether the microalbumin to creatinine ratio (Uma/Ucr) in the first-morning urine samples correlates with the microalbumin content in the 24-hour urine collection.METHODS:
59 urine samples from 59 type 2 diabetic patients were analyzed for Uma/Ucr, and for 24-hour urine microalbumin that were successively collected.RESULTS:
Daily microalbumin excretion varied from 2.4 to 168.7 mg/24 hr with a median value of 22.9 mg, and Uma/Ucr ranged from 3.4 to 200 g/mg with a median value of 29.0 g/mg. An excellent correlation was found between the microalbumin excretion measured from the 24-hour urine collections and the first-morning urine Uma/Ucr ratio (R=0.93, P<0.001). All patients that excreted more than 30 mg albumin in the 24-hour urine samples also had an Uma/Ucr of more than 30 g/mg. Patients who had less than 30 g/mg of Uma/Ucr were unlikely candidates for microalbuminuria.CONCLUSIONS:
This study indicates that measurements of Uma/Ucr in first-morning urine samples are a simple and reliable alternative to measurements of the urinary albumin excretion rate in the 24-hour urine collections.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Creatinina
/
Nefropatias Diabéticas
/
Coleta de Urina
Limite:
Humanos
Idioma:
Coreano
Revista:
The Korean Journal of Laboratory Medicine
Ano de publicação:
2003
Tipo de documento:
Artigo