A study on the changes of sebaceous gland activity during aging by analysis of skin surface lipids / 대한피부과학회지
Korean Journal of Dermatology
; : 912-919, 1993.
Artigo
em Coreano
| WPRIM (Pacífico Ocidental)
| ID: wpr-32807
Biblioteca responsável:
WPRO
ABSTRACT
BACKGROUND:
The human sebaceous glands have long been known to change their activity with aging. Downing and his co-workers state that the ratio of wax ester/cholesterol+cholesterol ester in the skin surface lipids might be a good index for sebaceous gland acti ity.OBJECTIVE:
Our purpose was to evaluate the effects of aging on the sebaceous gland activity and relative skin surface lipid composition by using thin layer chromatography.METHOD:
Skin surface lipids of anterior chest from 65 healthy Korean indivisuals were collected by using the cup method. Skin surface lipid were separated and meaurd by thin layer chromatographic analysis.RESULTS:
The sebaceous gland activity, vrhich was expressed by tlie ratio wax ester/[cholesterol+cholesterol ester] showed a ilistinct change from infancy to senescenc. The curve of the ratio makes a peak in the third decade and decreases with advancing age.CONCLUSION:
This result disclosed that sebaceous gland activity iaifected by advancing age in Koreans and can be used as one of the biologic markers of aging.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Glândulas Sebáceas
/
Pele
/
Tórax
/
Envelhecimento
/
Biomarcadores
/
Cromatografia em Camada Fina
Limite:
Humanos
Idioma:
Coreano
Revista:
Korean Journal of Dermatology
Ano de publicação:
1993
Tipo de documento:
Artigo