Polymorphism and multiplex amplification of 3 X-chromosome specific short tandem repeat loci / 中华医学遗传学杂志
Chinese Journal of Medical Genetics
; (6): 233-235, 2004.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-328911
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To devise a multiplex PCR system of three X-chromosome specific short tandem repeat (X-STR) loci and study the genetic polymorphism.</p><p><b>METHODS</b>DXS6799, DXS6804 and DXS6854 were amplified simultaneously using a multiplex system and were typed by polyacrylamide gel electrophoresis and silver staining.</p><p><b>RESULTS</b>A total of 262 male and 255 female individuals from Guangdong Han population were tested; each locus showed 7 alleles. 73 haplotypes were detected in the male individuals. The haplotype diversity reached 0.9674.</p><p><b>CONCLUSION</b>The 3 X-STR multiplex system is relatively abundant in polymorphic information for forensic identification and paternity testing.</p>
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Paternidade
/
Polimorfismo Genético
/
Haplótipos
/
Amplificação de Genes
/
Mapeamento Cromossômico
/
Sequências de Repetição em Tandem
/
Cromossomos Humanos X
Limite:
Feminino
/
Humanos
/
Masculino
Idioma:
Chinês
Revista:
Chinese Journal of Medical Genetics
Ano de publicação:
2004
Tipo de documento:
Artigo