Anterior lumbar intervertebral fusion with artificial bone in place of autologous bone / 华中科技大学学报(医学)(英德文版)
Journal of Huazhong University of Science and Technology (Medical Sciences)
; (6): 300-301, 2003.
Artigo
em Inglês
| WPRIM (Pacífico Ocidental)
| ID: wpr-330923
Biblioteca responsável:
WPRO
ABSTRACT
The feasibility of anterior lumbar intervertebral fusion with artificial bone in place of autogenous bone was investigated. Porous hydroxyapatite (HA)/ZrO2 ceramics loading bone morphogenetic protein (BMP) were implanted after removal of lumbar vertebral disc in rabbits. The adjacent intervertebral discs were also removed by the same way and autogenous illic bone was implanted. SEM observation and biomechanical test were carried out. Compound bone had a bit lower osteoinductive activity than autogenous bone by SEM (Osteoinductive activity of artificial bone in 12 weeks was the same as that of autogenous bone in 9 weeks). Biomechanical test revealed that compound bone had lower anti-pull strength than autogenous bone (P < 0.001), but there was no significant difference in anti-pull strength between compound bone at 12th week and autogenous bone at 9th week (P > 0.05). It was concluded that compound bone could be applied for anterior spinal fusion, especially for those patients who can't use autogenous bone.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Fusão Vertebral
/
Traumatismos da Coluna Vertebral
/
Cirurgia Geral
/
Materiais Biocompatíveis
/
Fosfatos de Cálcio
/
Durapatita
/
Proteínas Morfogenéticas Ósseas
/
Implantes Experimentais
/
Usos Terapêuticos
/
Hidroxiapatitas
Limite:
Animais
Idioma:
Inglês
Revista:
Journal of Huazhong University of Science and Technology (Medical Sciences)
Ano de publicação:
2003
Tipo de documento:
Artigo