Study on the relationship between polymorphism of ApoE gene and TCM syndrome type of primary hyperlipemia / 中国中西医结合杂志
Chinese Journal of Integrated Traditional and Western Medicine
; (12): 38-41, 2006.
Article
em Zh
| WPRIM
| ID: wpr-331757
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To study the relationship between the polymorphism of ApoE gene and TCM syndrome type of primary hyperlipemia.</p><p><b>METHODS</b>ApoE genotype of 102 patients with hyperlipemia was detected by gene PCR sequencing.</p><p><b>RESULTS</b>A total of five genotypes were detectable, they were E2/2, E3/3, E4/4, E2/3 and E3/4. The frequency of E3/4 + E4/4 and epsilon4 allelotype detected in the patients of Gan-Shen Yin deficiency syndrome type were significantly higher than those in patients of Pi-Shen Yang-deficiency type or of phlegm stagnation type (P < 0.05, P < 0.01), and which in patients of Qi-stagnation caused blood stasis type were significantly higher than those in patients of phlegm stagnation type ( P < 0.05).</p><p><b>CONCLUSION</b>Polymorphism of ApoE gene is related in a certain degree to TCM syndrome type of primary hyperlipemia.</p>
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Apolipoproteínas E
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Polimorfismo Genético
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Deficiência da Energia Yin
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Diagnóstico
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Diagnóstico Diferencial
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Genética
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Genótipo
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Hiperlipidemias
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Medicina Tradicional Chinesa
Tipo de estudo:
Diagnostic_studies
Limite:
Adult
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Aged
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Aged80
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Female
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Humans
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Male
Idioma:
Zh
Revista:
Chinese Journal of Integrated Traditional and Western Medicine
Ano de publicação:
2006
Tipo de documento:
Article