Purification of total flavones from Morus alba L.by macroporous adsorbents and kinetic model for the process / 浙江大学学报·医学版

ABSTRACT

<p><b>OBJECTIVE</b>To establish the separation and purification technology for the total flavones from Morus alba L.(MTF), and present a kinetic model for this process.</p><p><b>METHODS</b>Three types of macroporous adsorbents were tested to separate and purify MTF, and to evaluated by adsorption capacity, elution ratio and product purity. The curves of dynamic adsorption-elution process was plotted and the kinetic equations were presented.</p><p><b>RESULT</b>Among three types of macroporous adsorbents, the NKA-9 type showed better property with the adsorption capacity of 43.4 mg.g(-1)and the elution ratio of 98.2%. The purity of MTF product reached to 58.2 % in the technological conditions following extract sample concentration of 20 mg.ml(-1), 6 times washing water and elution reagent of 70% ethanol. The adsorbent could be used for 4 times repeatedly. The kinetic equation was y=u(1 - e(-kx)).</p><p><b>CONCLUSION</b>The NKA-9 type of macroporous absorbent is suitable to purify the MTF.</p>