Research progress of N-Myc roles in hematopoiesis and hematologic malignancies / 中国实验血液学杂志
Journal of Experimental Hematology
; (6): 503-507, 2013.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-332748
Biblioteca responsável:
WPRO
ABSTRACT
N-Myc oncogene plays an important role in the process of hematopoietic cell proliferation and differentiation in embryos. Once the body suffers from hematologic malignancies, the expression of N-Myc would increase and significantly associate with disease progression. In this article the structure of N-Myc, the regulatory mechanism in the different hematopoietic lineages, the interaction in each signal pathways, the transgenic animal model of overexpression, and intervention by drugs are reviewed.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Proteínas Proto-Oncogênicas c-myc
/
Neoplasias Hematológicas
/
Hematopoese
/
Metabolismo
Limite:
Humanos
Idioma:
Chinês
Revista:
Journal of Experimental Hematology
Ano de publicação:
2013
Tipo de documento:
Artigo