Bicarbonate secretion by the female reproductive tract and its impact on sperm fertilizing capacity / 生理学报
Acta Physiologica Sinica
; (6): 115-124, 2005.
Article
em En
| WPRIM
| ID: wpr-334197
Biblioteca responsável:
WPRO
ABSTRACT
The luminal fluid environment of the female reproductive tract is considered critical for the sperm to undergo a series of molecular events leading to the final acquisition of their fertilizing capacity. It has been shown that the fluid in the female reproductive tract contains high content of HCO3- and it plays an important role in sperm functions including sperm motility, capacitation, hyperactivation and acrosome reaction. This review summarizes the effects of HCO3- on sperm functions occurring in the female reproductive tract and discusses the transport mechanisms involved in mediating uterine HCO3- secretion. New evidence is also presented to show possible cause of female infertility due to defective HCO3- transporting mechanism.
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Fisiologia
/
Capacitação Espermática
/
Interações Espermatozoide-Óvulo
/
Útero
/
Bicarbonatos
/
Secreções Corporais
/
Fertilização
/
Metabolismo
Limite:
Animals
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Acta Physiologica Sinica
Ano de publicação:
2005
Tipo de documento:
Article