Ooplasmic transfer: problems and prospects / 南方医科大学学报
Journal of Southern Medical University
; (12): 1079-1082, 2006.
Artigo
em Inglês
| WPRIM (Pacífico Ocidental)
| ID: wpr-334991
Biblioteca responsável:
WPRO
ABSTRACT
Cytoplasmic transfer between human oocytes, which represents a complete cytoplasmic exchange, has been performed recently as a means to improve the outcome of assisted reproduction and becomes a hotspot of researches. Many studies have indicated that mitochondria in the oocytoplasm obviously affect fertilization of the oocytes and early embryo development. However, ooplasmic transfer can lead to mitochondrial DNA heteroplasmy and the prospect of mitochondrial heteroplasmy and its potential problems necessitate further studies. The authors reviews the ooplasmic transfer, the relation between ooplasm and fertilization and embryo development, and the mitochondrial heteroplasmy. The authors also propose a new theory of "reverse cloning technique".
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Oócitos
/
Transplante
/
Fertilização in vitro
/
Doação de Oócitos
/
Biologia Celular
/
Citoplasma
/
Desenvolvimento Embrionário
/
Métodos
Limite:
Feminino
/
Humanos
Idioma:
Inglês
Revista:
Journal of Southern Medical University
Ano de publicação:
2006
Tipo de documento:
Artigo