Effect of preemptive analgesia with flurbiprofen axetil on patient-controlled intravenous analgesia with tramadol in patients undergoing postburn plastic surgery / 南方医科大学学报
Journal of Southern Medical University
; (12): 1255-1256, 2009.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-336095
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To observe the preemptive analgesic effect of flurbiprofen axetil for post-operative pain relief.</p><p><b>METHODS</b>Sixty ASA class I or II patients undergoing postburn plastic surgery were randomly assigned into two groups to receive intravenous administration of 100 mg flurbiprofen axetil (group F, n=30) and 10 ml intravenous saline (group C, n=30) 30 min before surgery. After the operation, all the patients received patient-controlled intravenous analgesia (PCIA) with tramadol for pain relief. The postoperative analgesic effect was assessed by visual analog scales (VAS) at 1, 2, 4, 8, 12 and 24 h after surgery, with tramadol requirements and the adverse effects were recorded.</p><p><b>RESULT</b>At 1, 2, 4, and 8 h after the operation, the patients in group F showed significantly lowered VAS scores as compared with the patients in group C (P<0.05). The requirement of tramadol was also significantly less in group F than in group C (182.9-/+37.4 vs 227.3-/+49.8 mg, P<0.05). No significant difference was found in the adverse effects between the two groups.</p><p><b>CONCLUSION</b>Flurbiprofen axetil can produce preemptive analgesia and reduce the tramadol dose during postoperative PCIA in patients undergoing postburn plastic operations.</p>
Texto completo:
Disponível
Contexto em Saúde:
ODS3 - Meta 3.5 Prevenção e tratamento do consumo de substâncias psicoativas
Problema de saúde:
Abuso de Opioides
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Dor Pós-Operatória
/
Cirurgia Geral
/
Cirurgia Plástica
/
Fatores de Tempo
/
Tramadol
/
Queimaduras
/
Anti-Inflamatórios não Esteroides
/
Flurbiprofeno
/
Analgesia Controlada pelo Paciente
/
Usos Terapêuticos
Limite:
Adulto
/
Feminino
/
Humanos
/
Masculino
Idioma:
Chinês
Revista:
Journal of Southern Medical University
Ano de publicação:
2009
Tipo de documento:
Artigo