Preliminary study on chemical constituents seperated from Cayratia japonica / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To study effective active constituents of Cayratia japonica,a genuine herbal medicine from Fujian.</p><p><b>METHOD</b>Such chromatographic methods as Macroporous, Sephadex LH-20, ODS and normal phase silica gel column chromatography were adopted to separate the chemical components of C. japonica.</p><p><b>RESULT</b>Thirteen compounds were obtained, and their structures were identified by analyzing multiple spectral data as luteolin(1), apigenin(2), triethyl citrate-(3), 3-formylindole(4), esculetin(5), bis(2-ethylhexyl)-phthalate(6), calendin(7), ethyl-trans-3,4-dihydr-oxycinnamate(8), luteolin7-O-D-glucoside(9),5-hydroxy-3,4-dimethyl-5-pentyl-2(5H-furanone(10),ethyl-3,4-dihydroxybenzoate(11), eriodictyol(12) and daucosterol(13).</p><p><b>CONCLUSION</b>Among them, compounds 3-8 and 10-12 were separated from the plant for the first time.</p>