Advances in researches on the relationship between single nucleotide polymorphism and prostate cancer / 中华男科学杂志
National Journal of Andrology
; (12): 605-610, 2005.
Article
em Zh
| WPRIM
| ID: wpr-339469
Biblioteca responsável:
WPRO
ABSTRACT
Single nucleotide polymorphism (SNP) has been regarded as the third generation of heredity markers with many marked characteristics. It has been developed many new experimental techniques for detecting SNP in recent years, such as TaqMan probe technique, gene chip technique, denaturing high performance liquid chromatograph, matrix assisted laser desorption ionization-time off light mass spectrometry and minisequencing technique. Great progress has been made in researches on human tumors with SNP as heredity markers. This article reviews the genes and SNP related to the development of prostate cancer, including prostate specific antigen response component, enzymes, hormones and their receptors, cell cycle regulating protein, cytokines, adhesion molecules, vitamins and so on, and aims to explore the possible mechanism of the disease.
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Neoplasias da Próstata
/
Antígeno Prostático Específico
/
Polimorfismo de Nucleotídeo Único
/
Genética
Limite:
Humans
/
Male
Idioma:
Zh
Revista:
National Journal of Andrology
Ano de publicação:
2005
Tipo de documento:
Article