Determination of luteolin and luteolin-7-beta-D-glucoside in Chrysanthemum morfolium Ramat. from different collection time by RP-HPLC / 浙江大学学报·医学版

ABSTRACT

<p><b>OBJECTIVE</b>To observe the content variation of luteolin and luteolin-7-beta-D-glucoside in Chrysanthemum morifolium Ramat. (CMR) from different collection time.</p><p><b>METHODS</b>RP-HPLC was used to analyze these two components in CMR collected in 2001 and 2002.</p><p><b>RESULT</b>The content of luteolin was significantly lower than that of luteolin-7-beta-D-glucoside. Furthermore, the former showed no marked changes during collection, while the latter did not varied markedly in early collection but decreased significantly in later collection.</p><p><b>CONCLUSION</b>The content of luteolin-7-beta-D-glucoside reflects the quality of Chrysanthemum morifolium Ramat. more viably than that of luteolin.</p>