Achievement and progress of dynamic culture conditions on the construction of engineered blood vessel substitutes / 生物医学工程学杂志
Journal of Biomedical Engineering
; (6): 716-719, 2008.
Article
em Zh
| WPRIM
| ID: wpr-342758
Biblioteca responsável:
WPRO
ABSTRACT
Dynamic culture conditions serve as a critical factor in constructing physiologically functional blood vessel substitutes. With the development of tissue engineering, many experiments have verified the hypothesis that proper dynamic conditions are important for cells' behaving ways such as attachment, proliferation, differentiation and the remodeling of the extracellular matrix. By means of simulating the physiological dynamic conditions, one can enhance cell growth and extracellular matrix remodeling, and further improve the function of engineered vessel. In this paper is reviewed the current state of dynamic culture conditions provided for tissue engineering vessel graft, including the effects of different dynamic culture conditions on the proliferation of vascular cells and the remodeling of extracellular matrix. The use of bioreactor in constructing tissue engineering blood vessels and the effects of dynamic culture environments are also discussed with respect to the biological properties of vascular grafts.
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Artéria Pulmonar
/
Fenômenos Biomecânicos
/
Prótese Vascular
/
Adesão Celular
/
Diferenciação Celular
/
Células Cultivadas
/
Técnicas de Cultura de Células
/
Reatores Biológicos
/
Biologia Celular
/
Engenharia Tecidual
Limite:
Animals
Idioma:
Zh
Revista:
Journal of Biomedical Engineering
Ano de publicação:
2008
Tipo de documento:
Article