Effect of compound glycyrrhizin on peripheral T-lymphocyte subset in AIDS patients / 中华男科学杂志
National Journal of Andrology
; (12): 598-601, 2006.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-343565
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To probe the effect and mechanism of Compound Glycyrrhizin in treating AIDS.</p><p><b>METHODS</b>Forty AIDS patients were randomly divided into a treatment group and a control group, both treated with HAART. In addition, the former was given Compound Glycyrrhizin for 6 months, and the CD4+ T count and the expressions of CD8+ and HLA-DR on the surface of peripheral blood lymphocytes (PBL) were studied before and after the treatment.</p><p><b>RESULTS</b>After 6 months of treatment, the expressions of CD8+ and CD38+ of PBL in the treatment group [(6.6 +/- 2.1)%] were found lower than in the control [(11.4 +/- 3.8)%] (t = 5.043, P < 0.01) and CD4+ T count [(243.6 +/- 91.2) x 10(6)/L vs (170.8 +/- 55.7) x 10(6)/L] rose more significantly (t = 3.045, P < 0.01).</p><p><b>CONCLUSION</b>Compound Glycyrrhizin can lower the expression of active T-lymphocyte subset, inhibit HIV and help immune reconstitution.</p>
Texto completo:
Disponível
Contexto em Saúde:
ODS3 - Saúde e Bem-Estar
Problema de saúde:
Meta 3.3: Acabar com as doenças tropicais negligenciadas e combater as doenças transmissíveis
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Antígenos HLA-DR
/
Subpopulações de Linfócitos T
/
Síndrome da Imunodeficiência Adquirida
/
Contagem de Linfócito CD4
/
Fármacos Anti-HIV
/
Ácido Glicirrízico
/
Terapia Antirretroviral de Alta Atividade
/
Usos Terapêuticos
/
Tratamento Farmacológico
/
Alergia e Imunologia
Limite:
Adolescente
/
Adulto
/
Feminino
/
Humanos
/
Masculino
Idioma:
Chinês
Revista:
National Journal of Andrology
Ano de publicação:
2006
Tipo de documento:
Artigo