Etiologic analysis of globozoospermia: a 1-case report / 中华男科学杂志

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the etiologic factors of globozoospermia.</p><p><b>METHODS</b>Routine semen analysis, sperm DNA special staining and chromosomal karyotype detection of peripherical blood lymphocytes were performed in a globozoospermia patient.</p><p><b>RESULTS</b>Round-headed spermatozoa were lack of acrosome and the acrosin activity was low. Meanwhile, there was an additional band located in the Y chromosomal short arm.</p><p><b>CONCLUSION</b>Lack of acrosome, low acrosin activity and abnormality of chromosome may be the main reasons for globozoospermia.</p>