Effect of vitamin C antioxidative protection on human red blood cells / 中国实验血液学杂志
Journal of Experimental Hematology
; (6): 1106-1108, 2005.
Article
em Zh
| WPRIM
| ID: wpr-343816
Biblioteca responsável:
WPRO
ABSTRACT
In order to investigate the effect of antioxidants on human blood, vitamin C was selected and added into plastic blood storage bags with CPD, and stored at 25 degrees C. During 6 days of storage, some indexes as ATP, SOD, MDA, K(+) concentration and superoxide radicals were detected and were compared with control group, The results showed that ATP and SOD activity in whole blood with vitamin C during 6 days of storage was higher then that in control group (P < 0.05, P < 0.01), the MDA and plasma K(+) concentrations in stored whole blood with vitamin C during 6 days of storage were lower than that in control group (P < 0.05, P < 0.01), the superoxide radical concentrations in stored whole blood with vitamin C decreased lower than that in control group (30%). The conclusion was made that vitamin C increases activities of ATP and SOD, decreases concentrations of MDA, plasma K(+) and superoxide radicals during blood preservation.
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Farmacologia
/
Potássio
/
Ácido Ascórbico
/
Superóxido Dismutase
/
Fatores de Tempo
/
Sangue
/
Preservação de Sangue
/
Trifosfato de Adenosina
/
Biologia Celular
/
Eritrócitos
Limite:
Humans
Idioma:
Zh
Revista:
Journal of Experimental Hematology
Ano de publicação:
2005
Tipo de documento:
Article