Effects of calcium phosphate cement/eucommia ulmoides extracts compound on cell proliferation and adhesion of MC3T3E1 osteoblasts in vitro / 浙江大学学报·医学版

ABSTRACT

<p><b>OBJECTIVE</b>To observe the effects of calcium phosphate cement/eucommia ulmoides extracts compound (CPC/EUE) on cell proliferation and adhesion of MC3T3E1 osteoblasts in vitro.</p><p><b>METHODS</b>Cultured MC3T3E1 osteoblasts were divided into 5 groups blank control, CPC/EUE 0, 0.152, 0.304 and 0.608 mg/ml. 3H-TdR and scan electronic microscopy (SEM) were used to observe the cell growth, proliferation and adhesion.</p><p><b>RESULT</b>The CPC/EUE compound enhanced the cell growth, proliferation and adhesion. The concentrations of 0.152 mg/ml, 0.304 mg/ml were more significant in enhancing the cell proliferation rate (P<0.05).</p><p><b>CONCLUSION</b>CPC/EUE can promote the cell growth, proliferation and adhesion of the osteoblasts.</p>