Treatment of inflammatory bowel disease with Chinese drugs administered by both oral intake and retention enema / 中国结合医学杂志
Chinese journal of integrative medicine
; (12): 222-228, 2010.
Article
em En
| WPRIM
| ID: wpr-344914
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To study the clinical effect of Chinese drugs administered by both oral intake and retention enema on inflammatory bowel diseases (IBD).</p><p><b>METHODS</b>Adopting a randomized controlled design, 78 patients were assigned to three groups: 26 patients in group A treated with Chinese drugs given by both oral intake and retention enema, 27 in group B with Chinese drugs given by retention enema only, and 25 in group C with given Western medicine. The changes before and after a 30-day treatment of the patients' symptoms (including diarrhea, abdominal pain, mucous or pus-bloody stool), colonoscopic examination scores and histopathology of the colonic membrane were observed.</p><p><b>RESULTS</b>Group A showed the best outcomes in all the aspects of clinical comprehensive effectiveness. Improvements in the main symptoms, colonoscopic scores and histopathology of the colonic membrane were significantly different from those in groups B and C, respectively (P<0.05). Meanwhile comparisons between groups B and C showed insignificant differences (P>0.05); group B was better in ameliorating tenesmus (P<0.05).</p><p><b>CONCLUSION</b>Through the use of Chinese drugs administered by both oral intake and retention enema to treat IBD, which combined external-internal therapies for both overall regulation and local management, it was confirmed that the Chinese medicine could embody the therapeutic principle of attending to both disease-diagnosis and syndrome-differentiation.</p>
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Patologia
/
Farmacologia
/
Medicamentos de Ervas Chinesas
/
Doenças Inflamatórias Intestinais
/
Administração Oral
/
Colonoscopia
/
Resultado do Tratamento
/
Colo
/
Usos Terapêuticos
/
Tratamento Farmacológico
Tipo de estudo:
Clinical_trials
Limite:
Adult
/
Humans
Idioma:
En
Revista:
Chinese journal of integrative medicine
Ano de publicação:
2010
Tipo de documento:
Article