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The drug-resistant mechanism of clinical non-fermenting bacilli producing IMP-1 metalloenzyme / 生物医学工程学杂志
Artigo em Chinês | WPRIM (Pacífico Ocidental) | ID: wpr-346051
Biblioteca responsável: WPRO
ABSTRACT
A total of 50 clinical imipenem-resistant isolates of Pseudomonas aeruginosa and Acinetobacter baumannii were subjected to the ceftazidime-2- mercaptoethanol -double-disk synergy test and to the PCR assays with primers specific for bla(IMP-1). After the process of sequencing the positive one to identify the results, PCR analysis was conducted with primers specific for class 1 integrons. For synergy test, 28 isolates gave positive results, among which were 27 Pseudomonas aeruginosa and Acinetobacter baumannii. Only one Pseudomonas aeruginosa was found to carry bla(IMP-1), and bla(Int1) at the same time. This is the first ascertainment of IMP-1 producing Pseudomonas aeruginosa isolate carrying bla(IntI1) in West China, which is of significance to the research on the clinical spread of these drug-resisitant genes.
Assuntos
Texto completo: Disponível Base de dados: WPRIM (Pacífico Ocidental) Assunto principal: Farmacologia / Pseudomonas aeruginosa / Beta-Lactamases / Testes de Sensibilidade Microbiana / Ceftazidima / Imipenem / Farmacorresistência Bacteriana Múltipla / Acinetobacter baumannii / Fermentação / Genética Idioma: Chinês Revista: Journal of Biomedical Engineering Ano de publicação: 2007 Tipo de documento: Artigo
Texto completo: Disponível Base de dados: WPRIM (Pacífico Ocidental) Assunto principal: Farmacologia / Pseudomonas aeruginosa / Beta-Lactamases / Testes de Sensibilidade Microbiana / Ceftazidima / Imipenem / Farmacorresistência Bacteriana Múltipla / Acinetobacter baumannii / Fermentação / Genética Idioma: Chinês Revista: Journal of Biomedical Engineering Ano de publicação: 2007 Tipo de documento: Artigo
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