Progress in genome-scale metabolic network: a review / 生物工程学报
Chinese Journal of Biotechnology
; (12): 1340-1348, 2010.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-351588
Biblioteca responsável:
WPRO
ABSTRACT
Dozens of genome-scale metabolic networks have been reconstructed by integrating information from various databases on genes, proteins, metabolites and validated by experiment data from the literature. The reconstructed networks can be used to quantitatively investigate the interactions between components of a biological system at a system level. Such theoretical study could help us understand the organization principle of the large scale network and thus provide guidance to strain optimization through metabolic engineering technology. In this review, we evaluate the methods for the reconstruction, analysis and application of genome-scale metabolic networks. The difficulties and perspectives on this emerging research field are also discussed.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Fisiologia
/
Biotecnologia
/
Microbiologia Industrial
/
Engenharia Genética
/
Genômica
/
Redes e Vias Metabólicas
/
Métodos
Idioma:
Chinês
Revista:
Chinese Journal of Biotechnology
Ano de publicação:
2010
Tipo de documento:
Artigo