Clinical research of 120 cases of primary small intestine malignant tumor / 南方医科大学学报

ABSTRACT

<p><b>OBJECTIVE</b>To study the clinical and pathological features, diagnosis, therapy and prognosis of primary small intestine malignant tumor.</p><p><b>METHODS</b>A retrospective analysis was performed on the clinical data from the 120 cases of primary small intestine malignant tumor.</p><p><b>RESULTS</b>Abdominal pain, gastrointestinal bleeding, anemia, abdominal mass and jaundice were the main clinical features. The pathology was confirmed by abdominal X-ray, gastrointestinal barium, CT, MRI, endoscopy and surgical exploration. Most tumors originated in the duodenum (54.1%), and adenocarcinoma (55.8%) was the main pathological type. The median survival time of the patients was 19.2 months and the 1-year survival rate was 55.4%. Chemotherapy did not seem to significantly improve the 1-year survival rate of the patients (P=0.842).</p><p><b>CONCLUSION</b>Primary small intestine malignant tumors lack specific clinical manifestations and surgical resection should be performed as early as possible.</p>