Anti-inflammatory effects of flavonoids from Lonicera japonica Thunb. Caprifoliaceae in combination with ?-amylase

ABSTRACT

In vitro, flavonoids from Lonicera japonica Thunb flavonoids stimulate the catalysis of hydrolysis starch. This stimulating effect depended on the concentration of Lonicera japonica flavonoid but their in vitro stimulations weren’t strong. The anti-inflammatory effects were stronger when combining flavonoid with -amylase on dextran-induced edema mouse legs. So active catalysis stimulation of -amylase could be associated with anti-inflammation process; with unclear mechanisms. This result suggested the need of further research of anti-inflammatory drugs according to combine of traditional medicine and anti-inflammatory enzyme