Improvement in Symptoms and QuantiFERON TB-2G Test Results after Isoniazid Administration in a Patient with Normal Routine Tests Results / General Medicine

ABSTRACT

Diagnosis is difficult in patients who complain of slight fever without objective abnormalities. It is not rare that patients without signs of typical <i>Mycobacterium tuberculosis</i> (TB) infection have a delayed TB diagnosis. It has been reported that the QuantiFERON TB-2G test is useful for diagnosing latent TB infection. We report a patient who suffered from sweating, body weight loss, and a fever of less than 37.5C without abnormalities in routine tests. Except for his complaints, only QuantiFERON TB-2G testing suggested his illness, after which he was successfully treated with isoniazid administration. QuantiFERON TB-2G testing might be useful to diagnose patients with slight fever when TB is suspected but a conventional workup is not diagnostic.