Relationship between environmental exposures,genetic polymorphism of NAT2 and colorectal cancer / 肿瘤研究与临床
Cancer Research and Clinic
; (6): 89-91, 2010.
Article
em Zh
| WPRIM
| ID: wpr-379963
Biblioteca responsável:
WPRO
ABSTRACT
Objective To explore the relationship between NAT2 genetic polymorphism and the risk of colorectal cancer. Methods A hospital-based case-control study was conducted and polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) method was used to detect its genotypes.Results The frequency of NAT2 slow genotype was 19.58% in cases with colorectal cancer compared.with increased the risk for developing colorectal cancer and their OR were 2.16(95% CI:1.31~3.54).Conclusion The results suggest that NAT2 genetic polymorphism is associated with colorectal canoer susceptibility.People with NAT2 slow genotype have higher coloreetal cancer risk.
Texto completo:
1
Base de dados:
WPRIM
Tipo de estudo:
Observational_studies
/
Risk_factors_studies
Idioma:
Zh
Revista:
Cancer Research and Clinic
Ano de publicação:
2010
Tipo de documento:
Article