Determination of drug release in vitro of atractylenolide Ⅰ liposome by RP-HPLC / 国际中医中药杂志
International Journal of Traditional Chinese Medicine
; (6): 533-534, 2010.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-385989
Biblioteca responsável:
WPRO
ABSTRACT
Objective To establish a RP-HPLC method for the determination of drug release in vitro of atractylenolide Ⅰ liposomes. Methods The release behavior of the drug from liposomes was studied by the third method for dissolution. ZORBAX C18 column (4.6 mm × 250 mm, 5 μm) was used with a mobile phase of Methanol-Acetonitrile-0.2% from liposomes in vitro fitted the log-normal distribution equation and had a property of sustained release. Conclusion The method is simple, fast and selective. It is suitable for the determination of release profile in vitro of atractylenolide Ⅰ liposomes.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
International Journal of Traditional Chinese Medicine
Ano de publicação:
2010
Tipo de documento:
Artigo