Decorin and signaling pathways of cancer / 国际肿瘤学杂志

ABSTRACT

Decorin is a member of small leucine - rich proteoglycan( SLRP) family. Decorin plays an important role in proliferation, differentiation, and migration of carcinoma cells by regulating virous signaling pathways. Decorin will be a novel target for cancer therapy for its role such as regulating cytokines, immunosupression,and inhibiting cancer cells growth and metastasis.