The effect of GRP78 on cancer / 国际外科学杂志
International Journal of Surgery
; (12): 127-130, 2010.
Article
em Zh
| WPRIM
| ID: wpr-391545
Biblioteca responsável:
WPRO
ABSTRACT
The glucose-regulated protein78 (GRP78) is a member of the heat-shock protein 70 (HSP70) family and responsible for cellular homeostasis. GRP78 is highly expressed in various tumors. It plays an im-portant role in tumor proliferation, survival, metastasis, and drug resistance. Suppression of GRP78 in tumors could enhance cancer treatment. Inhibition of GRP78 in tumors may provide a noval approach toward cancer therapy.
Texto completo:
1
Base de dados:
WPRIM
Idioma:
Zh
Revista:
International Journal of Surgery
Ano de publicação:
2010
Tipo de documento:
Article