Kiss-1 gene and metastasis of malignant tumor / 国际肿瘤学杂志

ABSTRACT

Kiss-1 gene is an anti-oncogene which is correlative with the genesis and progress of various human malignant tumors.it plays an important role in process of tumor invasion and metastasis. Kiss-1 gene is associated closely with metastasis of melanoma,breast cancer,gastric carcinoma,esophageal cancer and differentiated thyroid carcinoma and so on,but the mechanism is not fully elucidated. Therefore,the detection of Kiss-1 gene expression will be valuable for the treatment and prognosis of malignant tumor.