Investigation on medical compliance in patients with chronic hepatitis B and an analysis of influence factors / 中华全科医师杂志

ABSTRACT

As to evaluating the medical compliance of patients with chronic hepatitis B (CHB) and the influence factors, information of 163 patients with CHB treated with lamivudine were collected by using the self-designed questionnaire, and the medical compliance and influencing factors of the patients were acquired by the research followed, and the prognosis and allocation were also observed. The results showed the medical compliance in 77.3% of patients with CHB was good, and in 22.7% patients was poor. After following-up for 2 years, the negative rates of HBV DNA and HBeAg shown in patients with good medical compliance were 78.6% and 46.0%, respectively,showing a significantly higher rate than in those with poor medical compliance, which having the rate of 37.8% and 21.6%, respectively (P<0.01). We suggested that there should be a correlation between the medical compliance of patients with CHB and the prognosis.