The genetic immunization in mice with three constructs of Toxoplasma gondii SAG1 gene / 热带医学杂志
Journal of Tropical Medicine
; (12): 3-9, 2001.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-411769
Biblioteca responsável:
WPRO
ABSTRACT
Three forms of the major surface antigen (SAG1)of Toxoplasma gondii, that is the membrane form, the secrete form and the intracellular form, were constructed and used to immunize BALB/c mice. The humoral response in the mice immunized with the membrane form and the secrete form of SAG1 appeared earlier and stronger than those mice immunized with the intracellular form. Result from the challenging infection demonstrated that the protection in the mice immunized with the membrane and the secrete forms was also stronger than in the mice immunized with the intracellular form. We suggest that the immune efficiency of the three forms of SAG1 in the mouse model is different.
Texto completo:
Disponível
Contexto em Saúde:
Doenças Negligenciadas
Problema de saúde:
Doenças Negligenciadas
/
Zoonoses
Base de dados:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Journal of Tropical Medicine
Ano de publicação:
2001
Tipo de documento:
Artigo