Effect of p38MAPK in icariin induced osteoblast differentiation / 中华内分泌代谢杂志
Chinese Journal of Endocrinology and Metabolism
; (12): 122-124, 2011.
Article
em Zh
| WPRIM
| ID: wpr-413808
Biblioteca responsável:
WPRO
ABSTRACT
This paper was aimed to investigate the effects of icariin on the expression of p38 mitogen activated protein kinase(MAPK)protein in rat osteoblasts cultured in vitro, to elucidate the signal transduction of icariin in preventing and treating osteoporosis. The results showed that p38MAPK could be activated by icariin within 5min, and Cbfal could also be upregulated, and SB203580, an inhibitor of p38MAPK pathway, could partly inhibit Cbfal upregulation by icariin.
Texto completo:
1
Base de dados:
WPRIM
Idioma:
Zh
Revista:
Chinese Journal of Endocrinology and Metabolism
Ano de publicação:
2011
Tipo de documento:
Article