Advances of RNAi in HPV16 E6/E7 of cervical cancer / 国际肿瘤学杂志
Journal of International Oncology
; (12): 300-303, 2011.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-414589
Biblioteca responsável:
WPRO
ABSTRACT
RNAi is a process of effective gene silencing. Human papillomaviruses 16 (HPV16), as the most prevalent genotype of cervical cancer, encodes the E6 and E7 oncogenes, which is pivotal for maintenance of malignant phenotypes. Recently, some significant advances have been obtained in RNA interfering effect on HPV16 E6/E7. In vitro, it has been developed more effective vector systems and screened for more specific targeted sequences. In vivo, the corresponding animal models have been established, which lay a good foundation for the clinical research.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Journal of International Oncology
Ano de publicação:
2011
Tipo de documento:
Artigo