A review on regulation of drug transporters during inflammation / 药学学报
Acta Pharmaceutica Sinica
; (12): 773-9, 2011.
Article
em Zh
| WPRIM
| ID: wpr-415014
Biblioteca responsável:
WPRO
ABSTRACT
Drug metabolism will change significantly during inflammation, including the reduction of expression and activity of many drug metabolizing enzymes and transporters. Body would release a series of inflammatory cytokines which can regulate drug metabolizing enzymes. Recent studies have revealed that drug transporters are also regulated by the cytokines with obvious species difference. Mechanism studies show that several transcription factors play important roles during the signal pathways of regulation. This review focuses on the progress in the regulation of drug transporters during inflammation.
Texto completo:
1
Base de dados:
WPRIM
Idioma:
Zh
Revista:
Acta Pharmaceutica Sinica
Ano de publicação:
2011
Tipo de documento:
Article