Meta-analysis of mycophenolate mofetil versus cyclophosphamide for diffuse proliferative lupus nephritis / 国际儿科学杂志
International Journal of Pediatrics
; (6): 208-211, 2012.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-418322
Biblioteca responsável:
WPRO
ABSTRACT
ObjectiveTo estimate the application of mycophenolate mofetil (MMF) and cyclophosphamide(CTX) intravenous pulse therapy on diffuse proliferative lupus nephritis (DPLN).MethodPubMed,Medline,EMBASE and CNKI were searched from the establishment of the database.Meta-analysis of 14 comparative studies on MMF and CTX in treatment of DPLN was performed,taking the remission,the relapse,the death of MMF and CTX for DPLN as primary efficacy variable,mean while taking the herpes zoster as safety evaluating indicator.ResultsMMF was better than CTX in remission rate ( P < 0.05 ).There was no difference between in incidence rate of the relapse,the death and the herpes zoste MMF and CTX for DPLN ( P > 0.05 ).ConclusionMMF was better than CTX on the efficacy and safety in DPLN.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Tipo de estudo:
Revisão sistemática
Idioma:
Chinês
Revista:
International Journal of Pediatrics
Ano de publicação:
2012
Tipo de documento:
Artigo