Glucagon-like peptide-1 receptor agonists, diabetes, obesity, and psoriasis / 中华内分泌代谢杂志
Chinese Journal of Endocrinology and Metabolism
; (12): 255-257, 2012.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-418634
Biblioteca responsável:
WPRO
ABSTRACT
More and more extrapancreatic actions of incretin-based therapies have been demonstrated and recently case reports have linked glucagon-like peptide-1 (GLP-1) receptor agouist therapy with the improvements in psoriasis.Psoriasis is a common skin disorder characterized by chronic inflammation.Epideminological studies have showed that patients with psoriasis exhibit increased rates of cardiovascular disease,obesity,and type 2 diabetes,owing probably to the enhanced local and (or) systemic inflammation.The observations of anti-inflammatory actions of GLP-1,which exerts direct and indirect actions on immune function,together with the improved psoriasis,offer new insights into the investigation of non-classical anti-inflammatory actions of incretin-based therapeutics and provide a new direction for the research of the novel clinical application of GLP-1.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Journal of Endocrinology and Metabolism
Ano de publicação:
2012
Tipo de documento:
Artigo