Expression of vascular endothelial growth factor and its receptor in the epididymal sperm of adolescent male rats / 中国组织工程研究
Chinese Journal of Tissue Engineering Research
; (53): 5221-5224, 2011.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-423792
Biblioteca responsável:
WPRO
ABSTRACT
BACKGROUND:
Vascular endothelial growth factor (VEGF) and its receptor fms-like tyrosine kinase-1 (Flt-1) have a very important position in the field of male reproduction. However, it is still unclear about their expression meaning and regulatory mechanism in the reproductive system.OBJECTIVE:
To study the expression and location of VEGF and Flt-1 in the epididymal sperm of adolescent male rats.METHODS:
The expression of VEGF and Flt-1 was detected in 10 adolescent SD rats. The concentration of the sperm was (30-40)×109/L. Immunofluorescent staining was used for VEGF and Flt-1 expression and location in the sperm. RESULTS ANDCONCLUSION:
Immunofluorescent staining showed that VEGF and Flt-1 were both localized in the acrosome of sperm head, as well as in the neck, middle and principal segment of sperm tail. Specific expression patterns of VEGF and Flt-1 in the sperm of rats display that they may participate in spermiotelcosis, relevant to movement, capacitation and acrosome reaction of the sperm.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Journal of Tissue Engineering Research
Ano de publicação:
2011
Tipo de documento:
Artigo