Effect of probiotics on patients with severe acute pancreatitis: A Meta analysis / 中华消化杂志
Chinese Journal of Digestion
; (12): 93-97, 2012.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-428302
Biblioteca responsável:
WPRO
ABSTRACT
Objective To explore the effect of probiotics on patients with severe acute pancreatitis.Methods Randomized controlled trials of probiotics in patients with severe acute pancreatitis were searched in Cochrane Library(2010),Medline(1966 to September 2010),China Academic Literature Full-text Database,Chinese Science and Technology Journal Database and WanFang Database between 1966 and September 2010.Evaluation of literature quality and data extraction were independently completed by two researchers.Data were analyzed with RevMan4.3 software.Results A total of 313 papers had been searched.After excluded duplicated and low-level paper,six articles were included in this study.The result showed that the infection rate(OR=0.88,95%CI[0.56,1.38])and mortality rate(OR=1.44,95%CI[0.78,2.64])of patients with severe acute pancreatitis in intervention group were not lower than control group,however the length of stay in hospital was shorter in intervention group than control group(WMD=-4.69,95% CI[-7.73,-1.65]).There was no significant difference between intervention group and control group in systemic inflammatory response syndrome(OR =1.33,95 % CI[0.63,2.83]),multiple organ failure (OR=1.50,95 % CI[0.89,2.52])and transfering to surgery department for further treatment(OR=0.92,95%CI[0.56,1.51]).Conclusion So far the studies indicated that probiotics could not lower the infection rate and mortality rate in patients with severe acute pancreatitis.Large sample and highquality randomized controlled trials are needed for further evaluation.
Texto completo:
Disponível
Contexto em Saúde:
ODS3 - Meta 3.4 Reduzir as mortes prematuras devido doenças não transmissíveis
Problema de saúde:
Doenças do Sistema Digestório
Base de dados:
WPRIM (Pacífico Ocidental)
Tipo de estudo:
Ensaio clínico controlado
/
Revisão sistemática
Idioma:
Chinês
Revista:
Chinese Journal of Digestion
Ano de publicação:
2012
Tipo de documento:
Artigo